Products

TOTAL SOLUTION

One-stop Solution for In-hospital BNCT Center

A New Generation NeuPex System

Neuboron's BNCT Total Solution

Neuboron's BNCT total solution combines the latest compact accelerator, high-performance beam shaping assembly, precise robotic positioning system for treatment, regional radiation monitoring system, efficient radioprotector, intelligent treatment planning system, boron-containing drugs for diagnosis and treatment, and relevant supporting subsystems. The solution helps physicians perform BNCT with ease for clinical and research purposes.

The upper level
The lower level
The upper level The lower level
1Control room
2Horizontal beam treatment rooms
3HEBL Room
4Accelerator room
5Accelerator control room
6Simulation positioning room
7Vertical beam treatment room
Control room

1Control room

Horizontal beam treatment rooms

2Horizontal beam treatment rooms

HEBL Room

3HEBL Room

Accelerator room

4Accelerator room

Accelerator control room

5Accelerator control room

Simulation positioning room

6Simulation positioning room

Vertical beam treatment room

7Vertical beam treatment room

NeuPex 系统

Innovative
NeuPex System

It is a compact AB-BNCT system that produces high-quality and stable neutron beam for clinical application. Its radiation protection design ensures personnel safety and maximizes space utilization. The system offers single or multiple treatment rooms to fit different environments and meet different clinical and reserach needs.

Hardware Systems

Beam Shaping Assembly

The double cone design effectively enhances beam intensity and multiplies the proportion of epithermal neutrons.

High-quality epithermal neutron beams allow for deep tumor treatment.

The intensity, energy spectrum and irradiation field of the neutron beams can be adjusted for treating tumors of various shapes and locations, to improve therapeutic effects and minimize unnecessary radiation exposure to the patient.

Beam Shaping Assembly

Dramatically increases the proportion of epithermal neutrons for deep tumor (depth > 11cm) treatment under a given condition

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The double cone design effectively enhances beam intensity and multiplies the proportion of epithermal neutrons.

High-quality epithermal neutron beams allow for deep tumor treatment.

The intensity, energy spectrum and irradiation field of the neutron beams can be adjusted for treating tumors of various shapes and locations, to improve therapeutic effects and minimize unnecessary radiation exposure to the patient.

On-Line beam monitoring & control System:

Ease to use: The one-button operation design makes it easy for medical physicists to perform treatment.

Comprehensive monitoring: On-line monitoring of beams, regional radiation and accessory equipment with multi-view visualization design offers intuitive access to the device status and operating data.

Real-time feedback: Real-time system error monitoring and real-time prompts for safe operations.

On-Line beam monitoring & control System:

user-friendly GUI, real-time data visualization, and comprehensive monitoring

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Ease to use: The one-button operation design makes it easy for medical physicists to perform treatment.

Comprehensive monitoring: On-line monitoring of beams, regional radiation and accessory equipment with multi-view visualization design offers intuitive access to the device status and operating data.

Real-time feedback: Real-time system error monitoring and real-time prompts for safe operations.

Accelerator:

Accelerator:

The compact, eco-friendly and reliable accelerator produces continuous and high-quality proton beam for BNCT. The accelerator is manufactured by our partner & supplier TLS.

Patient positioning system:

The humanized design with 7-axis rotating function enables the treatment couch to meet the requirements of different treatment positions for different patients and provide patients with comfortable treatment.

The control system enables not only fast and stable positioning but also adjustment based on patients' requirements, thus maximizing therapeutic effects.

The intelligent anti-collision system ensures the safety of medical staff and patients

Patient positioning system:

Sub-millimeter accuracy and six degrees of freedom allow for faster, safer and accurate patient positioning

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The humanized design with 7-axis rotating function enables the treatment couch to meet the requirements of different treatment positions for different patients and provide patients with comfortable treatment.

The control system enables not only fast and stable positioning but also adjustment based on patients' requirements, thus maximizing therapeutic effects.

The intelligent anti-collision system ensures the safety of medical staff and patients

Radiation safety and monitoring:

Patented special shielding materials and technology for BNCT.

Enable more effective radiation protection in limited space to save space without compromising safety.

Radiation is effectively contained within the controlled area while the operators are safe outside the controlled areas.

Radiation safety and monitoring:

Safe and controllable radiation
Patented shielding materials make efficient use of space

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Patented special shielding materials and technology for BNCT.

Enable more effective radiation protection in limited space to save space without compromising safety.

Radiation is effectively contained within the controlled area while the operators are safe outside the controlled areas.

Treatment Planning System

Intelligent medical image processing

Automatic import of DICOM images, multiple image processing and noise removal algorithms, support for a variety of Monte Carlo programs

Complete BNCT workflow

Multiple biological model libraries, definitions of ROI, blood-boron concentrations and relative biological effectiveness (RBE) of boron-containing drugs, automatic identification of radiation source path, automatic mapping of radiation source description and automatic mapping of collimator sizes

Dose calculation and visualization

Automatic calculation of physical and biological dose of various components, automatic generation and visualization of biologically equivalent dose, calculation of dose distribution at different radiation angles, and optimization of treatment plans

Targeted Boron Drugs

  • Therapeutic drug

    Boron-containing amino acid drug BPA New drug development

    Boron-containing amino acid drug BPA is the most widely used and the only recommended BNCT drug (approved in Japan in March 2020). Neuboron has independently developed a new BPA synthesis technique that makes for lower production costs, and local production.

    Including Boron-containing polymers coupled with monoclonal/polyclonal antibodies, liposome-encapsulated carborane-containing drugs, and next-generation boron drugs such as boron phosphate-loaded nanoparticles to enhance tumor targeting efficiency of the drugs, and expand the indications of BNCT.

    Boron-containing amino acid drug BPA
    New drug development
  • Diagnostic drug

    Independent  18F-BPA positron drug combined with PET-CT to evaluate drug distribution. Quickly and effectively determine whether the patient is suitable for BNCT treatment.

Technical Services

A professional BNCT team dedicated to clinical support

The team is committed to help medical Institutions with the construction of modern BNCT centers worldwide: providing customized products and services for research and clinical purposes, implementing cutting-edge technologies and supporting healthcare workers serve patients more efficiently and intently.

示范中心
THE 1ST AB-BNCT CENTER IN CHINA

Demonstration Center

China's first and World's largest

BNCT Clinical Demonstration Center and Training Base

A research center with continuous innovation capability

Neuboron is building China's first and world's largest AB-BNCT cancer treatment and clinical demonstration center with its proprietary BNCT systems and continuous innovation capability as well as quality medical resources from Xiamen Humanity Hospital. The center has two horizontal beam treatment rooms and one vertical beam treatment room to irradiate a variety of cancers (such as head, neck, chest, and abdomen).